1. Choose your Affinity Group

* Equal Opportunity / Affirmative Action

We serve Equal Opportunity Employers and are an Equal Opportunity Employer. The Professional Diversity Network has separate professional networking sites for different affinities, and in selecting the groups you identify with, you will be joined with those networks.

Note: Providing this information is strictly voluntary - you will not be penalized or subjected to adverse treatment. If you choose not to provide this information, simply select "Choose not to identify."

2. Choose Method
Sign in with LinkedIn
Sign in with Facebook

Tell us about yourself

Investigative Toxicologic Pathologist
at Vertex
Boston, MA

Investigative Toxicologic Pathologist
at Vertex
Boston, MA

Save or bookmark jobs as you go and access them anytime later with your account.



Job Description:

Preclinical Safety Assessment (PSA) is a global function responsible for the design and conduct of comprehensive nonclinical safety programs for the evaluation of Vertex therapies at all stages of discovery and development. Vertex Pharmaceuticals uses cutting edge science and technology to perform robust assessments of novel therapies for the treatment of the most serious diseases with unmet medical need. Our culture enables individual empowerment where We Wins, Fearless Pursuit of Excellence, and Innovation are more than just corporate values; they are part of our everyday lives.PSA pathologists have significant roles in the drug development process beginning in early discovery and continuing through the entire drug development value chain resulting in successful registration and marketing approval.

The Investigative Toxicologic Pathologist - Preclinical Safety Assessment will be responsible for:
  • Strategic and scientific leadership in the design, conduct and interpretation of pathology endpoints for animal model development, target identification/validation, and in vivo pharmacology and nonclinical biomarker development studies including the use of cutting-edge molecular diagnostic and digital imaging technologies as part of a newly-created discovery & investigative pathology group
  • Anatomic pathology evaluation of investigative pathology and regulatory toxicity studies from lead identification/optimization through registration and post-marketing including peer review of outsourced nonGLP and GLP toxicology studies
  • Expert scientific leadership in discovery, translational research, and regulatory nonclinical safety profiling activities as a key partner on cross-functional teams within Vertex, working with a high-functioning multidisciplinary team of preclinical safety and biomarker scientists including a Board-certified veterinary clinical pathologist and an extensive network of external consultants and contract research organizations
  • Participation in regulatory submission document preparation, poster presentations and scientific publications, including addressing queries from global health authorities
The position includes opportunities for potential additional roles including:
  • Preclinical safety representative on discovery and/or development project teams
  • Nonclinical safety evaluation of in-licensing opportunities supporting business development


  • DVM or equivalent and ACVP/ECVP board certification in veterinary anatomic pathology
  • PhD in a relevant scientific discipline is strongly preferred
  • 3+ years of work experience in Discovery and/or Toxicologic pathology in the pharmaceutical/biotechnology sector including the conduct of GLP peer reviews
  • Extensive practical experience using imaging technologies and molecular diagnostic pathology techniques to understand the pathologic basis of disease and support drug discovery and development
  • Demonstrated excellence in oral and written communications, critical thinking and issue resolution skills, and scientific collaboration, guidance, and mentoring of non-DVM scientists and laboratory associates

Similar Jobs

See All »

Other Jobs at Vertex

See All »